- Texas Highway 67 connects the town with Marfa 60 miles to the north.
- FM 170 comes into town from the Big Bend National Park area.
- Mexican Highway 16 connects the Chihuahuan state capital with Ojinaga, Presidio's somewhat larger sister city on the other side of the Rio Grande.
- Fort Leaton State Historic Site (Four miles out of town on farm road 170.). A 25-room compound constructed in 1848.
Since the last shop to cater to tourists closed a couple of years ago, the only interesting shopping is over the river in Ojinaga.
A lot more dining options can be found just across the border in Ojinaga.
- El Patio, 513 Oreilly St, ☎ +1 432 229 4409. Good Mexican food. Try their burritos.
- Big Bend National Park, and the near-ghost town of Terlingua are all within an hour's drive east on farm road 170.
- Big Bend Ranch State Park, 30 minutes east on FM 170. Texas' largest state park.
- Chinati Hot Springs, Box 67 Candelaria Route (off Ranch Road 170 about 40 miles northwest in the community of Ruidosa). Hot springs as well as trails into the canyons of the Chinati Range.
- Ojinaga is a larger city on the Mexican side of the border in the state of Chihuahua. It is perhaps the least spoiled of all the border towns and offers the visitor an experience like a Mexican interior town.
- Peguis Canyon is a breathtaking geological feature about 25 miles to the east on Mexican Highway 16.
- Shafter Historic Mining District, about 20 miles north on Highway 67. Adobe remnants of a silver mining community of the late 19th and early 20th centuries.
|Routes through Presidio|
|Fort Stockton ← Marfa ←||N S||→ → becomes → Ojinaga → Chihuahua|