How to Choose Chronic Fatigue Syndrome Medicines

Chronic fatigue syndrome is a disorder with complex symptoms. The main symptom, extreme fatigue, becomes worse with physical or mental activity but does not get better with rest or sleep. The cause is mostly unknown so there is no cure for chronic fatigue syndrome, though the symptoms can be managed. Symptoms are different for everyone, may come and go and include fatigue, muscle ache, lack of concentration, memory loss, headache, un-refreshing sleep, enlarged lymph nodes and joint paint without swelling. Other symptoms include, but are not limited to, exhaustion after exercise that lasts more than 24 hours, abdominal pain, chest pain, earache, nausea, chronic cough and chills or night sweats.


  1. Image titled Choose Chronic Fatigue Syndrome Medicines Step 1
    See your doctor to discuss the best option of treatment for your specific symptoms of chronic fatigue. Your doctor will be able to determine the right medicines for each symptom that is bothering you.
  2. Image titled Choose Chronic Fatigue Syndrome Medicines Step 2
    Decide whether you want to take medicine for your symptoms or if there is an alternative that can benefit you. Some symptoms of chronic fatigue can be alleviated from a change in habit.
    • Consider cognitive behavioral therapy, which helps you to cope with having chronic fatigue syndrome and can help you deal with the symptoms. Keeping a positive outlook and changing negative thoughts can help alleviate symptoms.
    • Think about exercise in a different way. Though exertion can make you excessively tired, mild, consistent exercise can actually alleviate symptoms of chronic fatigue syndrome. Exhaustion after exercise is typical with moderate exercise but mild exercise is recommended.
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    Determine your most pressing symptoms; the ones that are the most prominent. Make a list to help you look at it objectively. Dealing with and treating the more obvious symptoms can help you effectively deal with the minor ones.
    • Try over-the-counter pain medication, such as acetaminophen, aspirin or non-steroid anti-inflammatory pills to help alleviate the pain associated with chronic fatigue syndrome. Consider pain therapy from a pain specialist if over-the-counter pain medications do not work.
    • Talk with your doctor about antidepressants if you are feeling depressed. Your doctor may prescribe medicines such as amitriptyline, nortriptyline or fluoxetine, which can also help with any sleep disturbance you may be experiencing with chronic fatigue syndrome.
    • Consider medications such as clonazepam for dizziness, if you exhibit instability or trouble standing upright. You may also want to consider increasing fluid and salt intake before taking medicine to see if it helps alleviate the dizziness.


  • The medicines you take may have to be adjusted over time as your symptoms change.
  • Try over-the-counter allergy medicine if you are experiencing symptoms of allergies, such as runny nose.


  • Chronic fatigue syndrome affects everyone differently; your treatment may be different than others and what works for someone else may or may not work for you.

Things You'll Need

  • Doctor Appointment
  • Therapy
  • Over-the-Counter Pain Medication
  • Antidepressants
  • Orthostatic Instability Treatment

Article Info

Categories: Taking Pills and Medicine